See cytocast in action on our DEMO page.
Do you want to use our simulator? Get in touch with us.

Cytocast whole cell simulator© is a high-performance computing tool, which can transform how we handle drug treatments.
The predictions of Cytocast Whole Cell Simulator rely on the fact that most biological functions are performed by protein complexes. We can identify how patients respond to a treatment by simulating protein complex formation across multiple tissues .

Cytocast whole cell simulator© runs 4 main steps.

1. Generate the model

Patient specific molecular profile data is integrated with our proprietary database to build models of individual cells from various tissues of the patient.
Examples of data source for our model are:

  • Proteomics abundance from mass spectrometry for various tissue types
  • Gene-expression from RNA-sequencing
  • Single protein or gene measurements

Your data is not in the list? Contact us to find out if we can help you.
2. Select drug to test

Choose one of our predefined drug or upload your in-house drug-protein interactions. At this stage, we can only provide support for intracellular drugs, but this will be expanded shortly.

If you would like to know what we can do for your drug, please contact us.

3. Simulate the model

Here is where the magic happens!

The superfast, parallelized Cytocast algorithm is capable of simulating 100,000,000 proteins, and all existing protein-protein interactions, making it the most advanced human cell simulator on the market.

We perform multiple simulations to test the effects of each drug you selected on all requested tissue types..

4. Report predictions

At the end of simulation, we identify which protein complexes and protein-protein interactions were the most affected by the drug. These are used to identify the cellular phenotype changes that the drug caused on each tissue type. Based on these changes we can also suggest which treatment could be the most beneficial for the given patient.

2021-03-26T09:48:23+00:00
Go to Top